Item Type | Name |
Concept
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Tumor Cells, Cultured
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Academic Article
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Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
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Academic Article
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Attenuation of G2-phase cell cycle checkpoint control is associated with increased frequencies of unrejoined chromosome breaks in human tumor cells.
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Academic Article
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C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure.
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Academic Article
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Cross-talk between ceramide and PKC activity in the control of apoptosis in WEHI-231.
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Academic Article
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Footprinting of individual tumors and their variants by constitutive cytokine expression patterns.
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Academic Article
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Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor.
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Academic Article
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The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
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Academic Article
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Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
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Academic Article
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Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis.
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Academic Article
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Down-regulation of cell cycle control genes by ionizing radiation.
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Academic Article
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DNA double-strand break rejoining rates, inherent radiation sensitivity and human tumour response to radiotherapy.
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Academic Article
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Phosphorous metabolite and cell cycle kinetic response of two human squamous cell carcinomas to radiation.
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Academic Article
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Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis.
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Academic Article
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Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors.
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Academic Article
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Modulation of apoptotic response of a radiation-resistant human carcinoma by Pseudomonas exotoxin-chimeric protein.
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Academic Article
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The interaction of 5-fluorouracil, hydroxyurea, and radiation in two human head and neck cancer cell lines.
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Academic Article
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Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation.
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Academic Article
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The contribution of DNA ploidy to radiation sensitivity in human tumour cell lines.
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Academic Article
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Inhibition of phosphatidylinositol 3-kinase by c-Abl in the genotoxic stress response.
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Academic Article
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Activation of protein kinase C delta by the c-Abl tyrosine kinase in response to ionizing radiation.
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Academic Article
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Combined effects of angiostatin and ionizing radiation in antitumour therapy.
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Academic Article
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Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.
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Academic Article
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Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation.
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Academic Article
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Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
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Academic Article
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Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1.
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Academic Article
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NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity.
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Academic Article
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Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.
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Academic Article
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Role for p300 in stabilization of p53 in the response to DNA damage.
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Academic Article
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Cytogenetic evidence of the multistep origin of head and neck squamous cell carcinomas.
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Academic Article
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Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
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Academic Article
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Treatment of head and neck and esophageal xenografts employing Alimta and concurrent ionizing radiation.
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Academic Article
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Enhanced eradication of local and distant tumors by genetically produced interleukin-12 and radiation.
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Academic Article
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Function for p300 and not CBP in the apoptotic response to DNA damage.
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Academic Article
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In vitro and in vivo activity of protein kinase C inhibitor chelerythrine chloride induces tumor cell toxicity and growth delay in vivo.
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Academic Article
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Anti-angiogenic cues from vascular basement membrane collagen.
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Academic Article
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Down-regulation of ceramide production abrogates ionizing radiation-induced cytochrome c release and apoptosis.
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Academic Article
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Quantitative analysis of DNA array autoradiographs.
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Academic Article
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TNFerade Biologic: preclinical toxicology of a novel adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene.
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Academic Article
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Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.
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Academic Article
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Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma.
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Academic Article
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Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
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Academic Article
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Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model.
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Academic Article
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The use of a genetically engineered herpes simplex virus (R7020) with ionizing radiation for experimental hepatoma.
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Academic Article
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Inhibition of glioma cell growth and tumorigenic potential by CCN3 (NOV).
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Academic Article
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Angiostatin potentiates cyclophosphamide treatment of metastatic disease.
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Academic Article
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The novel isocoumarin 2-(8-hydroxy-6-methoxy-1-oxo-1H-2-benzopyran-3-yl) propionic acid (NM-3) induces lethality of human carcinoma cells by generation of reactive oxygen species.
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Academic Article
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Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.
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Academic Article
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Tumour-endothelium interactions in co-culture: coordinated changes of gene expression profiles and phenotypic properties of endothelial cells.
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Academic Article
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Transcriptional control of viral gene therapy by cisplatin.
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Academic Article
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Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor.
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Academic Article
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STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
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Academic Article
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Posttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localize.
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Academic Article
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Endothelial cells co-cultured with wild-type and dominant/negative p53-transfected glioblastoma cells exhibit differential sensitivity to radiation-induced apoptosis.
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Academic Article
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Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay.
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Academic Article
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Two prostate carcinoma cell lines demonstrate abnormalities in tumor suppressor genes.
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Academic Article
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Cellular and molecular aspects of human tumor radioresistance.
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Academic Article
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Mechanisms of X-ray-mediated protooncogene c-jun expression in radiation-induced human sarcoma cell lines.
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Academic Article
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Forphenicinol enhances the antitumor effects of cyclophosphamide in a model of squamous cell carcinoma.
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Academic Article
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p53 gene mutations and abnormal retinoblastoma protein in radiation-induced human sarcomas.
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Academic Article
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Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma.
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Academic Article
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Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
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Academic Article
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Sensitivities of NIH/3T3-derived clonal cell lines to ionizing radiation: significance for gene transfer studies.
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Academic Article
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Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
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Academic Article
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Radioresistant tumor cell lines derived from head and neck radiation failures.
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Academic Article
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Southern analysis of human head and neck cancer cells for homologous sequences using yeast gamma repair genes.
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Academic Article
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Epidermal growth factor receptor gene amplification and expression in head and neck cancer cell lines.
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Academic Article
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Radioresistant tumor cells are present in head and neck carcinomas that recur after radiotherapy.
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Academic Article
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Faster repair of DNA double-strand breaks in radioresistant human tumor cells.
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Academic Article
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Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells.
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Academic Article
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Ionizing radiation stimulates a Grb2-mediated association of the stress-activated protein kinase with phosphatidylinositol 3-kinase.
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Academic Article
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Comparative analysis of the inherent radiosensitivity of ovarian carcinoma.
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Academic Article
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p56/p53lyn tyrosine kinase activation in mammalian cells treated with mitomycin C.
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Academic Article
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Chromosome changes characterizing in vitro response to radiation in human squamous cell carcinoma lines.
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Academic Article
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Effect of Bcl-2 on ionizing radiation and 1-beta-D-arabinofuranosylcytosine-induced internucleosomal DNA fragmentation and cell survival in human myeloid leukemia cells.
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Academic Article
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The role of paclitaxel in the treatment of head and neck cancer.
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Academic Article
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Clonal interactions in a human squamous cell carcinoma.
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Academic Article
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Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
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Academic Article
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Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation.
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Academic Article
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Ionizing radiation induces rapid tyrosine phosphorylation of p34cdc2.
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Academic Article
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Local gene delivery of tumor necrosis factor alpha can impact primary tumor growth and metastases through a host-mediated response.
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Academic Article
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Ionizing radiation activates transcription of the EGR1 gene via CArG elements.
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Academic Article
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Spatial and temporal control of gene therapy using ionizing radiation.
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Academic Article
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Ketoconazole attenuates radiation-induction of tumor necrosis factor.
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Academic Article
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Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine.
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Academic Article
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Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells.
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Academic Article
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Tumor endothelial inflammation predicts clinical outcome in diverse human cancers.
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Academic Article
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Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase.
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Academic Article
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Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.
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Academic Article
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The role of intracellular calcium in the cellular response to ionizing radiation.
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Academic Article
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Molecular targets to overcome radioresistance.
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Academic Article
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Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326.
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Academic Article
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Tumor necrosis factor-alpha-based gene therapy enhances radiation cytotoxicity in human prostate cancer.
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Academic Article
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Ionizing radiation improves survival in mice bearing intracranial high-grade gliomas injected with genetically modified herpes simplex virus.
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Academic Article
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Antitumor interaction of short-course endostatin and ionizing radiation.
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Academic Article
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Tumor production of angiostatin is enhanced after exposure to TNF-alpha.
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Academic Article
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Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.
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Academic Article
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The interaction between recombinant human tumor necrosis factor and radiation in 13 human tumor cell lines.
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Academic Article
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Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
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Academic Article
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Genetic radiotherapy overcomes tumor resistance to cytotoxic agents.
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Academic Article
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p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
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Academic Article
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A link between calcitriol and bone resorption.
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Academic Article
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Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.
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Academic Article
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RIG-I-like receptor LGP2 protects tumor cells from ionizing radiation.
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Academic Article
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EPR oxygen images predict tumor control by a 50% tumor control radiation dose.
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Academic Article
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JAK2 Inhibitor SAR302503 Abrogates PD-L1 Expression and Targets Therapy-Resistant Non-small Cell Lung Cancers.
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Academic Article
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ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response.
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